Epidemiology of primary hyperparathyroidism
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چکیده
Incidence The incidence has been increasing in many countries since the seventies [1; 2]. In some countries a peak incidence was reached after which the incidence declined to the same levels as were seen before the incidence started to increase [2]. This has been interpreted as the presence of a large “pool” of hitheto undiagnosed mild or asymptomatic patients, who are then diagnosed until the “pool” is emptied and the incidence decreases to the “true” incidence [2]. In Denmark an increase has also been seen, but no peak seems to have been reached [1]. However, the most recent numbers are from 1999, where approximately 250-300 new patients were diagnosed each year [1]. Among the patients approximately 60% underwent surgical treatment, i.e. approximately 150-180 surgeries per year for primary hyperparathyrpoidism [1]. In 2004 a total of approximately 350 parethyroid surgeries were performed in Denmark including surgical treatment of secondary hyperparathyrpoidism in patients with uremia (http://www.sst.dk/Indberetning%20og%20statistik/Sundhedsdata/Download_sundhedsstatistik/Pla nmateriale/LPR/DSNS.aspx). In the US between 23% and 50% [3] of patients undergo surgery, i.e. considerably less than in Denmark, probably due to more with mild disease. In Denmark the incidence among women as increased more than in men [1] leading to a larger percentage of patients being women over time. Also the age of patients has increased meaning that the average patient at present is likely to be a woman aged 60 years or more [1].
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تاریخ انتشار 2013